Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TRPC5 | Q9UL62 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149464 | 0.87 | LMNA (0.70) | LMNAMAPK1TRPC5TP53POLB | |
| SCHEMBL31052942 | 0.78 | LMNA (0.49) | LMNAMAPK1TRPC5TP53POLB | |
| SCHEMBL7015123 | 0.76 | LMNA (0.66) | LMNAMAPK1TP53POLBHIF1A | |
| SCHEMBL5272670 | 0.75 | PDE4A (0.65) | LMNAMAPK1POLBSMN1; SMN2PDE4A | |
| SCHEMBL31042911 | 0.75 | TP53 (0.46) | LMNAMAPK1TRPC5TP53TRPC4 | |
| SCHEMBL16059155 | 0.74 | POLB (0.55) | LMNAMAPK1TRPC5TP53POLB | |
| SCHEMBL7015175 | 0.73 | LMNA (0.62) | LMNAMAPK1TRPC5POLBHIF1A | |
| SCHEMBL7018390 | 0.73 | LMNA (0.69) | LMNAMAPK1TP53POLBHIF1A | |
| SCHEMBL556077 | 0.73 | SMN1; SMN2 (0.74) | LMNAMAPK1TP53POLBHIF1A | |
| SCHEMBL20561174 | 0.72 | LMNA (1.00) | LMNAMAPK1TP53POLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663640-A1 | XANTHINE COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024164818-A1 | XANTHINE COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2024-08-15 | — | — | WO | disclosed |
| CN-118459461-A | Xanthine compound and application thereof | 中国科学院上海药物研究所 | 2024-08-09 | — | — | CN | disclosed |