SCHEMBL31043231

SCHEMBL31043231

C[C@H](NC(=O)[C@@H](N)CC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 11/20 0.38
▸ PTPN1 P18031 2/20 0.36
▸ PSMB5 P28074 1/20 0.36
▸ BACE1 P56817 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30814959 0.89 ACE (0.36) RENPSMB5
SCHEMBL30815070 0.89 ACE (0.36) RENPSMB5
SCHEMBL31043223 0.84 PTPN1 (0.40) RENPTPN1BACE1
SCHEMBL30815021 0.83 OPRD1 (0.36) PSMB5
SCHEMBL30163259 0.82 MDM4 (0.44) PTPN1PSMB5
SCHEMBL30163241 0.82 ACE (0.42) —
SCHEMBL30811214 0.82 MME (0.41) —
SCHEMBL30451367 0.81 ACE (0.41) REN
SCHEMBL25854495 0.80 REN (0.45) REN
SCHEMBL30811185 0.79 MME (0.43) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240319146-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS PEPTISTAR INC. (JP) 2024-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240319146-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS HDGF, VIP, NPPA REN 2263/4885PTPN1 4090/4885PSMB5 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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