Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043874 | 0.88 | L3MBTL1 (0.44) | MAPTL3MBTL1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL31043987 | 0.88 | L3MBTL1 (0.44) | MAPTNPSR1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31044019 | 0.87 | SMN1; SMN2 (0.43) | MAPTNPSR1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31029157 | 0.85 | MAPT (0.48) | MAPTNPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31043684 | 0.85 | MAPT (0.48) | MAPTNPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31043762 | 0.84 | RAB9A (0.60) | MAPTNPSR1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31043769 | 0.82 | KMT2A (0.61) | MAPTNPSR1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31043782 | 0.80 | SMN1; SMN2 (0.59) | MAPTL3MBTL1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL31043650 | 0.80 | SMN1; SMN2 (0.59) | MAPTNPSR1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31043578 | 0.80 | NPC1 (0.45) | MAPTNPSR1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | NAMPT, SIRT1, NNT | MAPT 766/4885NPSR1 795/4885L3MBTL1 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.