Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043936 | 0.88 | MAPT (0.49) | L3MBTL1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31043874 | 0.86 | L3MBTL1 (0.44) | L3MBTL1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31029072 | 0.85 | PHGDH (0.44) | MAPTSMN1; SMN2NPSR1GAASCD | |
| SCHEMBL31044020 | 0.85 | PHGDH (0.44) | MAPTSMN1; SMN2NPSR1GAASCD | |
| SCHEMBL31044019 | 0.85 | SMN1; SMN2 (0.43) | L3MBTL1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31043835 | 0.83 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2LMNAKMT2ARAB9A | |
| SCHEMBL31043762 | 0.82 | RAB9A (0.60) | L3MBTL1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31043769 | 0.78 | KMT2A (0.61) | L3MBTL1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31043554 | 0.78 | EPHX2 (0.54) | L3MBTL1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL31043578 | 0.78 | NPC1 (0.45) | MAPTSMN1; SMN2LMNAKMT2AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | NAMPT, SIRT1, NNT | L3MBTL1 4526/4885MAPT 766/4885SMN1; SMN2 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.