Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SOD1 | P00441 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044829 | 0.88 | TLR8 (0.43) | HSD17B10MAPK1GSK3AGSK3BALDH1A1 | |
| SCHEMBL20668004 | 0.84 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KDM4EPRKCIPOLB | |
| SCHEMBL31045119 | 0.82 | TLR8 (0.47) | HSD17B10MAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL31044856 | 0.82 | LMNA (0.42) | HSD17B10MAPK1GSK3AGSK3BALDH1A1 | |
| SCHEMBL20667921 | 0.82 | KDM4E (0.42) | HSD17B10ALDH1A1KDM4EPRKCILMNA | |
| SCHEMBL31045366 | 0.80 | MAPK1 (0.43) | HSD17B10MAPK1ALDH1A1KDM4EPRKCI | |
| SCHEMBL20667985 | 0.80 | RAD52 (0.40) | HSD17B10MAPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL20667918 | 0.80 | HPGD (0.40) | HSD17B10ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL20667986 | 0.79 | TLR8 (0.41) | — | |
| SCHEMBL20659871 | 0.79 | KDM4E (0.37) | HSD17B10ALDH1A1KDM4EPRKCILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | G6PD, SDHA, NQO1 | HSD17B10 1017/4885MAPK1 2900/4885GSK3A 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.