Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991671 | 0.83 | ADORA2A (0.46) | ADORA1TMIGD3ADORA2A | |
| SCHEMBL20668057 | 0.80 | LMNA (0.50) | ADORA1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31045057 | 0.80 | FLT3 (0.41) | CYP1A2MEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL5118573 | 0.78 | PRKCI (0.41) | ADORA1MEN1KMT2AALDH1A1ADORA2A | |
| SCHEMBL31044906 | 0.77 | FLT3 (0.53) | MEN1KMT2AALDH1A1MAPTADORA2A | |
| SCHEMBL31044774 | 0.77 | CYP1A2 (0.36) | ADORA1TMIGD3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31045077 | 0.76 | ADORA3 (0.37) | ADORA1ALDH1A1ADORA2AADORA3ADORA2B | |
| SCHEMBL31044873 | 0.76 | ADORA2A (0.43) | ADORA1KMT2AMAPTADORA2AADORA3 | |
| SCHEMBL31044817 | 0.75 | FLT3 (0.54) | ADORA1ALDH1A1HSD17B10ADORA2AADORA3 | |
| SCHEMBL31045127 | 0.75 | ADORA2A (0.42) | ADORA1ALDH1A1MAPTADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | G6PD, SDHA, NQO1 | ADORA1 3648/4885TMIGD3 4023/4885CYP1A2 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.