Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195386 | 0.82 | AKR1C1 (0.52) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL14441150 | 0.81 | AKR1C1 (0.50) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL31759345 | 0.79 | ADRA1D (0.40) | — | |
| SCHEMBL348690 | 0.79 | AKR1C1 (0.45) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL4503594 | 0.79 | APP (0.45) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL301150 | 0.78 | APP (0.61) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL31759497 | 0.77 | AKR1C1 (0.46) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL348779 | 0.77 | KMT2A (0.48) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL350266 | 0.75 | APP (0.58) | AKR1C1APPAKR1C3AKR1C2CYP2C19 | |
| SCHEMBL28317646 | 0.75 | AKR1C3 (0.55) | AKR1C1APPAKR1C3AKR1C2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680336-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
| WO-2024196788-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | AKR1C1 834/4885APP 163/4885AKR1C3 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.