SCHEMBL31048522

SCHEMBL31048522

Cn1cc(-c2cc(Cl)ccc2C=O)cn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR3 P22607 1/20 0.53
▸ KDR P35968 1/20 0.53
▸ ERN1 O75460 3/20 0.50
▸ GRM2 Q14416 2/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ PDK2 Q15119 1/20 0.42
▸ BRD4 O60885 1/20 0.41
▸ MET P08581 2/20 0.40
▸ ACVR1 Q04771 1/20 0.39
▸ KCNH2 Q12809 2/20 0.39
▸ KRAS P01116 1/20 0.39
▸ EGFR P00533 1/20 0.38
▸ ERBB2 P04626 1/20 0.38
▸ ERBB4 Q15303 1/20 0.38
▸ LRRK2 Q5S007 1/20 0.38
▸ PIK3CD O00329 1/20 0.38
▸ PIK3CA P42336 1/20 0.38
▸ PIK3CB P42338 1/20 0.38
▸ PI4KA P42356 1/20 0.38
▸ PIK3CG P48736 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19154127 0.82 ERN1 (0.53) ERN1GRM2BRD4METACVR1
SCHEMBL31048691 0.79 ERN1 (0.47) ERN1GRM2PDK2
SCHEMBL612984 0.78 BRD4 (0.53) ERN1GRM2PDK2BRD4
SCHEMBL16983114 0.75 FGFR3 (0.51) FGFR3KDRPDK2BRD4KCNH2
SCHEMBL15646275 0.75 SCN9A (0.47) ERN1TDP1METCNR1CNR2
SCHEMBL31048670 0.75 FGFR3 (0.44) FGFR3KDRPDK2METKCNH2
SCHEMBL31048672 0.75 FGFR3 (0.44) FGFR3KDRPDK2METKCNH2
SCHEMBL25280252 0.75 ERN1 (0.51) ERN1GRM2BRD4METACVR1
SCHEMBL16278740 0.75 ERN1 (0.48) ERN1GRM2BRD4ACVR1LRRK2
SCHEMBL21741531 0.75 FGFR3 (0.48) FGFR3KDRGRM2PDK2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662204-A2 TELOMERASE INHIBITOR COMPOUNDS Geron Corporation (US) 2025-12-17 — — EP disclosed
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2024-10-17 — — US disclosed
WO-2024168165-A2 TELOMERASE INHIBITOR COMPOUNDS GERON CORPORATION (US) 2024-08-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS TERT, POT1, TERF2 FGFR3 1349/4885KDR 2797/4885ERN1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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