SCHEMBL31048670

SCHEMBL31048670

Cn1cc(-c2cc(Cl)ccc2/C=N/[S+]([O-])C(C)(C)C)cn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR3 P22607 3/20 0.44
▸ KDR P35968 2/20 0.44
▸ PDK2 Q15119 2/20 0.40
▸ MET P08581 2/20 0.35
▸ SCN9A Q15858 2/20 0.34
▸ ALK Q9UM73 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ ERBB2 P04626 1/20 0.33
▸ ERBB4 Q15303 1/20 0.33
▸ KCNH2 Q12809 2/20 0.33
▸ FGFR4 P22455 2/20 0.32
▸ CNR1 P21554 1/20 0.32
▸ CNR2 P34972 1/20 0.32
▸ FGFR1 P11362 1/20 0.32
▸ FGFR2 P21802 1/20 0.32
▸ AXL P30530 1/20 0.32
▸ TYRO3 Q06418 1/20 0.32
▸ MERTK Q12866 1/20 0.32
▸ KRAS P01116 1/20 0.32
▸ PFKFB3 Q16875 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31048672 1.00 FGFR3 (0.44) FGFR3KDRPDK2METSCN9A
SCHEMBL14895580 0.78 ERN1 (0.42) PDK2EGFRERBB2ERBB4KCNH2
SCHEMBL14895579 0.78 ERN1 (0.42) PDK2EGFRERBB2ERBB4KCNH2
SCHEMBL21415683 0.78 ERN1 (0.42) PDK2EGFRERBB2ERBB4KCNH2
SCHEMBL31048645 0.77 PDK2 (0.34) FGFR3KDRPDK2CNR1CNR2
SCHEMBL29157506 0.77 ADRA1A (0.38) PDK2
SCHEMBL31048522 0.75 FGFR3 (0.53) FGFR3KDRPDK2METEGFR
SCHEMBL20424674 0.73 GRIN2D (0.44) —
SCHEMBL1888675 0.73 GRIN2D (0.44) —
SCHEMBL1888676 0.73 GRIN2D (0.44) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662204-A2 TELOMERASE INHIBITOR COMPOUNDS Geron Corporation (US) 2025-12-17 — — EP disclosed
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2024-10-17 — — US disclosed
WO-2024168165-A2 TELOMERASE INHIBITOR COMPOUNDS GERON CORPORATION (US) 2024-08-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS TERT, POT1, TERF2 FGFR3 1349/4885KDR 2797/4885PDK2 1916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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