SCHEMBL31048623

SCHEMBL31048623

CC=C1C(=O)N(CCc2ccccc2)c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.66
PARK7 Q99497 5/20 0.66
ALDH2 P05091 4/20 0.66
ALDH3A1 P30838 4/20 0.66
CASP3 P42574 1/20 0.55
PKM P14618 1/20 0.55
MAPT P10636 2/20 0.52
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GAA P10253 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CDC25A P30304 9/20 0.49
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12930286 0.83 CDC25A (0.67) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL16799085 0.80 ALDH1A1 (1.00) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL12930196 0.79 CDC25A (0.57) ALDH1A1PARK7ALDH2ALDH3A1MAPT
SCHEMBL1142116 0.77 CASP3 (0.86) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL29724090 0.77 CASP3 (0.86) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL15189265 0.75 ALDH1A1 (0.52) ALDH1A1PARK7ALDH2ALDH3A1CASP3
Dimethylamine SCHEMBL4418548 0.74 CASP3 (0.75) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL18403869 0.74 ALDH1A1 (0.53) ALDH1A1ALDH2ALDH3A1CASP3PKM
SCHEMBL2823268 0.73 ALDH1A1 (0.66) ALDH1A1PARK7ALDH2ALDH3A1CASP3
SCHEMBL13442858 0.71 CASP3 (1.00) ALDH1A1PARK7ALDH2ALDH3A1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662204-A2 TELOMERASE INHIBITOR COMPOUNDS Geron Corporation (US) 2025-12-17 EP disclosed
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2024-10-17 US disclosed
WO-2024168165-A2 TELOMERASE INHIBITOR COMPOUNDS GERON CORPORATION (US) 2024-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS TERT, POT1, TERF2 ALDH1A1 606/4885PARK7 1931/4885ALDH2 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.