SCHEMBL31048702

SCHEMBL31048702

CCc1ccccc1-c1cnn(C)c1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.54
▸ SMARCA2 P51531 1/20 0.47
▸ SMARCA4 P51532 1/20 0.47
▸ CHRM1 P11229 3/20 0.46
▸ CHRM3 P20309 1/20 0.46
▸ ADRA1A P35348 2/20 0.45
▸ PDK2 Q15119 3/20 0.45
▸ GRM2 Q14416 1/20 0.44
▸ CHRM5 P08912 1/20 0.43
▸ PDE9A O76083 1/20 0.43
▸ TRPA1 O75762 1/20 0.43
▸ LCK P06239 1/20 0.43
▸ BTK Q06187 1/20 0.43
▸ ADRA2A P08913 1/20 0.43
▸ EPHX2 P34913 1/20 0.42
▸ GRM5 P41594 1/20 0.41
▸ ALOX5AP P20292 1/20 0.41
▸ FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31181988 0.87 BRD4 (0.48) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL24359881 0.85 BRD4 (0.47) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL25022660 0.85 DPP4 (0.52) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL17794413 0.84 CFD (0.46) BRD4SMARCA2SMARCA4CHRM1ADRA1A
SCHEMBL20777560 0.82 SMARCA2 (0.47) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL17198730 0.82 BRD4 (0.43) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL20773248 0.82 CFD (0.52) BRD4SMARCA2SMARCA4CHRM1CHRM3
SCHEMBL28361331 0.81 TRPA1 (0.42) BRD4SMARCA2SMARCA4TRPA1GRM5
SCHEMBL21741531 0.78 FGFR3 (0.48) BRD4PDK2GRM2
SCHEMBL23753928 0.78 PDE9A (0.47) BRD4CHRM1CHRM5PDE9AALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662204-A2 TELOMERASE INHIBITOR COMPOUNDS Geron Corporation (US) 2025-12-17 — — EP disclosed
WO-2024168165-A2 TELOMERASE INHIBITOR COMPOUNDS GERON CORPORATION (US) 2024-08-15 — — WO disclosed
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