Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049367 | 0.71 | GRIN2B (0.36) | KDM4EL3MBTL1ALDH1A1NPSR1MAPT | |
| SCHEMBL26316767 | 0.65 | HRH1 (0.47) | L3MBTL1ALDH1A1MAPTTLR8TLR7 | |
| SCHEMBL7100687 | 0.64 | DAO (0.43) | L3MBTL1ALDH1A1MAPTTLR8TLR7 | |
| SCHEMBL31049269 | 0.64 | ALDH1A1 (0.35) | ALDH1A1HTT | |
| SCHEMBL31049371 | 0.62 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLB | |
| SCHEMBL45207 | 0.61 | TLR8 (0.44) | L3MBTL1ALDH1A1TLR8TLR7POLB | |
| SCHEMBL5691507 | 0.60 | TBXAS1 (0.47) | KDM4ENPSR1MAPTTLR8TLR7 | |
| SCHEMBL11440961 | 0.60 | TBXAS1 (0.47) | KDM4ENPSR1MAPTTLR8TLR7 | |
| SCHEMBL11438392 | 0.60 | TBXAS1 (0.47) | KDM4ENPSR1MAPTTLR8TLR7 | |
| SCHEMBL6114716 | 0.60 | TBXAS1 (0.47) | KDM4ENPSR1MAPTTLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |