Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049408 | 0.76 | IP6K1 (0.32) | IP6K1 | |
| SCHEMBL31049393 | 0.76 | ICMT (0.41) | LMNAPKM | |
| SCHEMBL31049268 | 0.70 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL31049571 | 0.70 | ALDH1A1 (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL31049503 | 0.70 | AR (0.32) | — | |
| SCHEMBL31049356 | 0.68 | CNR2 (0.47) | — | |
| SCHEMBL31049343 | 0.68 | GRIN2B (0.32) | — | |
| SCHEMBL31049305 | 0.67 | PLAU (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL30786269 | 0.66 | HRH3 (0.41) | — | |
| SCHEMBL31049532 | 0.64 | ALDH1A1 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |