Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221152 | 1.00 | LMNA (0.37) | LMNAALDH1A1MAPTHTTHPGD | |
| SCHEMBL14805476 | 0.73 | CDK1 (0.35) | — | |
| SCHEMBL1578052 | 0.70 | XDH (0.51) | PTGS2PTGS1 | |
| SCHEMBL21996606 | 0.69 | CCNA2 (0.33) | — | |
| SCHEMBL22346220 | 0.68 | MAPT (0.38) | LMNAALDH1A1MAPTHTTNPC1 | |
| SCHEMBL30975023 | 0.67 | CA12 (0.53) | LMNACA12CA1CA2CA9 | |
| SCHEMBL22346852 | 0.65 | RAPGEF4 (0.43) | ALDH1A1MAPTHTTHPGDMAPK1 | |
| SCHEMBL22084740 | 0.65 | SRC (0.49) | LMNAALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL25217566 | 0.64 | P2RX7 (0.44) | ALDH1A1MAPTHTTNPSR1KDM4E | |
| SCHEMBL2784840 | 0.64 | SRC (0.48) | LMNAALDH1A1MAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |