SCHEMBL3105290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1271891	0.89	KMO (0.61)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3118342	0.89	KMO (0.52)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3114736	0.85	KMO (0.49)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3114998	0.84	KMO (0.56)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3116377	0.84	PIK3CA (0.50)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3113412	0.79	KMO (0.50)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3100732	0.78	KMO (0.49)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3107368	0.77	HSD17B10 (0.57)	KMOALDH1A1KDM4ESMN1; SMN2NAPEPLD
	SCHEMBL6651425	0.77	POLB (0.64)	KMT2AKMOALDH1A1KDM4EMEN1
	SCHEMBL3113600	0.77	KMT2A (0.60)	KMT2AALDH1A1KDM4ESMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.