Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885149 | 0.79 | ACHE (0.47) | ACHEALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31053522 | 0.77 | TDP1 (0.38) | ALDH1A1TDP1LMNACHRNB4CHRNA3 | |
| SCHEMBL31053640 | 0.76 | HRH3 (0.45) | ACHE | |
| SCHEMBL4055295 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNAMEN1MAPT | |
| SCHEMBL30354927 | 0.75 | L3MBTL3 (0.41) | KMT2A | |
| SCHEMBL22875089 | 0.73 | ALDH1A1 (0.43) | ACHEEPHX2OPRL1ALDH1A1TDP1 | |
| SCHEMBL8252174 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TDP1LMNAMAPT | |
| SCHEMBL1752645 | 0.72 | KDM1A (0.50) | ALDH1A1TDP1LMNAMEN1KMT2A | |
| SCHEMBL1829575 | 0.72 | KDM1A (0.46) | ALDH1A1TDP1LMNAMEN1KMT2A | |
| SCHEMBL12988320 | 0.72 | L3MBTL1 (0.52) | ACHEOPRL1ALDH1A1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |