Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12176284 | 0.80 | MAPT (0.38) | MAPTALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL8989442 | 0.80 | ALDH1A1 (0.55) | HTTCYP1A2MAPTCYP3A4CYP2D6 | |
| SCHEMBL31055020 | 0.79 | CYP1A2 (0.34) | CYP1A2MAPTCYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL31587567 | 0.78 | MEN1 (0.45) | HTTMAPTALDH1A1NPSR1RAB9A | |
| SCHEMBL1000959 | 0.78 | L3MBTL1 (0.50) | HTTCYP1A2MAPTCYP3A4CYP2D6 | |
| SCHEMBL31588149 | 0.78 | KIF18A (0.40) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10891076 | 0.77 | POLB (0.54) | HTTCYP1A2MAPTCYP3A4CYP2D6 | |
| SCHEMBL12203 | 0.68 | CHRM2 (0.55) | HTTMAPTALDH1A1LMNA | |
| SCHEMBL7870381 | 0.66 | CYP1A2 (0.50) | HTTCYP1A2MAPTCYP3A4CYP2D6 | |
| SCHEMBL19955123 | 0.66 | ALDH1A1 (0.42) | HTTCYP1A2MAPTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459440-A | Preparation method and application of tetra-substituted aryl compound | 江苏普莱医药生物技术有限公司 | 2024-08-09 | — | — | CN | disclosed |