Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810712 | 0.91 | HTT (0.51) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL21351181 | 0.84 | L3MBTL1 (0.56) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL21333220 | 0.82 | HPGD (0.49) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL30285543 | 0.82 | HPGD (0.49) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL7956262 | 0.82 | ALDH1A1 (0.49) | HPGDLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL22801488 | 0.77 | KMT2A (0.43) | HPGDLMNAKMT2ACYP1A2KDM4E | |
| SCHEMBL31055419 | 0.77 | SMN1; SMN2 (0.56) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL31055396 | 0.77 | SMN1; SMN2 (0.56) | TSHRHTTL3MBTL1HPGDLMNA | |
| SCHEMBL21333350 | 0.77 | HPGD (0.53) | HTTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL21333348 | 0.77 | CYP1A2 (0.55) | TSHRHTTL3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |