Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26975356 | 0.92 | MEN1 (0.43) | NLRP3MAPTKDM4EALDH1A1PKM | |
| SCHEMBL22460318 | 0.91 | MEN1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL26975357 | 0.91 | — | — | |
| SCHEMBL31055698 | 0.82 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL22460320 | 0.81 | GAA (0.52) | NLRP3 | |
| SCHEMBL31055701 | 0.81 | NLRP3 (0.47) | NLRP3ALDH1A1 | |
| SCHEMBL31055693 | 0.79 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL31055695 | 0.79 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL31055707 | 0.78 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL31055732 | 0.78 | NLRP3 (0.47) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |