⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26975356 | 0.91 | MEN1 (0.43) | — | |
| SCHEMBL31055691 | 0.91 | NLRP3 (0.48) | — | |
| SCHEMBL22460318 | 0.90 | MEN1 (0.46) | — | |
| SCHEMBL26975355 | 0.86 | MEN1 (0.52) | — | |
| SCHEMBL26975465 | 0.83 | MEN1 (0.48) | — | |
| SCHEMBL7572034 | 0.82 | MEN1 (0.58) | — | |
| SCHEMBL7567422 | 0.81 | MEN1 (0.56) | — | |
| SCHEMBL26975353 | 0.81 | NLRP3 (0.51) | — | |
| SCHEMBL26975364 | 0.79 | NLRP3 (0.52) | — | |
| SCHEMBL26975351 | 0.79 | NLRP3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |
| US-11858922-B2 | Sulfonylureas and related compounds and use of same | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-02 | — | — | US | disclosed |
| US-11858922-B2 | Sulfonylureas and related compounds and use of same | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-02 | — | — | US | disclosed |