SCHEMBL31055822

SCHEMBL31055822

OB(O)Oc1ccc(-c2cccc(F)c2)cc1F

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.49
TAAR1 Q96RJ0 3/20 0.44
CYP11B2 P19099 2/20 0.40
PTPN1 P18031 1/20 0.39
PTGER2 P43116 4/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP11B1 P15538 1/20 0.37
DCLRE1B Q9H816 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
HTR2C P28335 1/20 0.36
PDK2 Q15119 1/20 0.36
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
FYN P06241 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29918704 0.86 MGLL (0.40) CYP11B2HSD17B1HSD17B2CYP17A1CYP11B1
SCHEMBL30523912 0.80 CES2 (0.39)
SCHEMBL2268873 0.80 CES2 (0.39)
SCHEMBL29255960 0.78 MGLL (0.40) HSD17B1HSD17B2CYP17A1PDGFRBPDGFRA
SCHEMBL27781801 0.78 FFAR4 (0.40)
SCHEMBL257807 0.75 ESR2 (0.55) ESR2TAAR1CYP11B2PTPN1HSD17B1
SCHEMBL12384885 0.73 ESR2 (0.49) ESR2TAAR1CYP11B2PTPN1HSD17B1
SCHEMBL18869467 0.73 TAAR1 (0.44) ESR2TAAR1CYP11B2PTPN1PTGER2
SCHEMBL761581 0.72 RARB (0.44) TAAR1CYP17A1
SCHEMBL31147883 0.72 TAAR1 (0.59) ESR2TAAR1CYP11B2PTPN1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118475572-A Compound for organic optoelectronic device, composition for organic optoelectronic device, and display device 三星SDI株式会社 2024-08-09 CN disclosed