Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562734 | 0.88 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL29010756 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL20835506 | 0.84 | CA12 (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL31056715 | 0.82 | NPC1 (0.47) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL19899909 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL19900051 | 0.80 | HPGD (0.48) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL31562843 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL31056786 | 0.78 | VCAM1 (0.50) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL19900095 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL19900078 | 0.78 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |