SCHEMBL31056715

SCHEMBL31056715

COC(=O)c1ccc(Br)c(C2OCCO2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NOTUM Q6P988 1/20 0.46
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
XDH P47989 1/20 0.42
ALDH1A1 P00352 5/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
ALOX15 P16050 2/20 0.41
MGLL Q99685 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20835506 0.84 CA12 (0.56) NPC1RAB9ASMN1; SMN2CA1CA2
SCHEMBL2530605 0.83 USP2 (0.39) RAB9ASMN1; SMN2NOTUMALDH1A1HPGD
SCHEMBL31056174 0.82 KDM4E (0.50) NPC1RAB9ASMN1; SMN2CA1CA2
SCHEMBL28282005 0.80 NOTUM (0.49) NPC1RAB9ASMN1; SMN2NOTUMCA1
SCHEMBL23708885 0.80 HPGD (0.46) NPC1RAB9ACA1CA2CA12
SCHEMBL31562734 0.79 KDM4E (0.54) NPC1RAB9ASMN1; SMN2CA1CA2
SCHEMBL31562843 0.79 ALDH1A1 (0.52) NPC1RAB9ASMN1; SMN2CA1CA2
SCHEMBL14691018 0.78 VCAM1 (0.53) SMN1; SMN2ALDH1A1HPGDMAPTGAA
SCHEMBL31056786 0.78 VCAM1 (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1HPGD
SCHEMBL31056487 0.77 SMN1; SMN2 (0.56) NPC1RAB9ASMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119688877-A Analysis and detection method for PFASs in environmental water sample 山东省科学院生态研究所(山东省科学院中日友好生物技术研究中心) 2025-03-25 CN disclosed
WO-2024178390-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2024-08-29 WO disclosed