Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642423 | 0.82 | HSD17B2 (0.45) | HSD17B2GAAPOLBALDH1A1MEN1 | |
| SCHEMBL31056099 | 0.81 | SLC22A12 (0.39) | GAAPOLBALDH1A1TSHRHTT | |
| SCHEMBL643091 | 0.80 | CA12 (0.55) | HSD17B2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13131915 | 0.78 | REN (0.44) | HSD17B2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL23217544 | 0.78 | ALDH1A1 (0.46) | HSD17B2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31026070 | 0.78 | ALDH1A1 (0.46) | HSD17B2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4273797 | 0.76 | HSD17B2 (0.55) | HSD17B2GAAPOLBALDH1A1MEN1 | |
| SCHEMBL18789684 | 0.73 | CA12 (0.62) | HSD17B2GAAPOLBALDH1A1MEN1 | |
| SCHEMBL23876967 | 0.71 | ALDH1A1 (0.59) | HSD17B2GAAPOLBALDH1A1MEN1 | |
| SCHEMBL6824879 | 0.70 | CTNNB1 (0.58) | HSD17B2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |