Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385881 | 1.00 | MAPT (0.48) | MAPTLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL9721947 | 0.89 | NOS3 (0.55) | MAPTLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL15972473 | 0.85 | MAPT (0.41) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL31569520 | 0.81 | MAPT (0.45) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL5446122 | 0.81 | MAPT (0.45) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL803098 | 0.81 | ALDH1A1 (0.47) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL28295982 | 0.81 | MAPT (0.46) | MAPTLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL8033158 | 0.80 | ALDH1A1 (0.43) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL28307339 | 0.79 | MAPT (0.38) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL12113957 | 0.79 | POLB (0.41) | MAPTLMNAHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |