Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307341 | 0.81 | HTT (0.45) | MAPTTDP1SMN1; SMN2LMNAHTT | |
| SCHEMBL28307340 | 0.80 | MAPT (0.39) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL31056280 | 0.79 | MAPT (0.48) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL15972473 | 0.79 | MAPT (0.41) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7385881 | 0.79 | MAPT (0.48) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28306205 | 0.77 | KMT2A (0.35) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL28307335 | 0.77 | HTT (0.38) | MAPTTDP1SMN1; SMN2LMNAHTT | |
| SCHEMBL31569520 | 0.76 | MAPT (0.45) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5446122 | 0.76 | MAPT (0.45) | MAPTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28306200 | 0.75 | GLP1R (0.33) | MAPTTDP1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |