Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055978 | 0.78 | CTSV (0.41) | FOLH1MCL1MEN1KMT2ASLC16A3 | |
| SCHEMBL31056382 | 0.78 | MCL1 (0.39) | FOLH1MCL1MEN1KMT2ACTSV | |
| SCHEMBL31056353 | 0.75 | MCL1 (0.39) | FOLH1MCL1MEN1KMT2ACTSV | |
| SCHEMBL31056034 | 0.74 | CTSV (0.41) | MEN1KMT2ACTSVCTSLLMNA | |
| SCHEMBL31056459 | 0.72 | FOLH1 (0.45) | FOLH1MCL1KDM4EALDH1A1CTSV | |
| SCHEMBL31056825 | 0.72 | MCL1 (0.47) | FOLH1MCL1KDM4EALDH1A1DHODH | |
| SCHEMBL31056217 | 0.72 | FOLH1 (0.48) | FOLH1MCL1KDM4EALDH1A1MEN1 | |
| SCHEMBL31056360 | 0.72 | CTSV (0.42) | FOLH1MCL1CTSVCTSLNR4A2 | |
| SCHEMBL31056045 | 0.72 | PTGER1 (0.50) | FOLH1MCL1KDM4EALDH1A1MEN1 | |
| SCHEMBL31056479 | 0.71 | MEN1 (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |