Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386011 | 0.88 | NPC1 (0.44) | CTSVCTSLMRGPRX4NPC1RXRA | |
| SCHEMBL31056825 | 0.85 | MCL1 (0.47) | FOLH1CTSVCTSLMCL1RXRA | |
| SCHEMBL31056217 | 0.85 | FOLH1 (0.48) | FOLH1MCL1MRGPRX4PTGER1KDM4E | |
| SCHEMBL31056045 | 0.85 | PTGER1 (0.50) | FOLH1CTSVCTSLMCL1MRGPRX4 | |
| SCHEMBL15968165 | 0.83 | FOLH1 (0.55) | FOLH1CTSVCTSLMCL1MRGPRX4 | |
| SCHEMBL31056247 | 0.82 | FOLH1 (0.43) | FOLH1CTSVCTSLMCL1PTGER1 | |
| SCHEMBL31055978 | 0.82 | CTSV (0.41) | FOLH1CTSVCTSLMCL1POLB | |
| SCHEMBL4464916 | 0.81 | FOLH1 (0.56) | FOLH1CTSVCTSLMCL1MRGPRX4 | |
| SCHEMBL31056082 | 0.81 | KDM1A (0.45) | S1PR5 | |
| SCHEMBL31055888 | 0.81 | ERN1 (0.43) | NPC1S1PR5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |