Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056402 | 0.89 | LMNA (0.43) | FOLH1ALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL31056459 | 0.85 | FOLH1 (0.45) | FOLH1ALDH1A1L3MBTL1MCL1KDM4E | |
| SCHEMBL31056045 | 0.85 | PTGER1 (0.50) | FOLH1ALDH1A1L3MBTL1MCL1KDM4E | |
| SCHEMBL31056825 | 0.85 | MCL1 (0.47) | FOLH1ALDH1A1L3MBTL1MCL1KDM4E | |
| SCHEMBL31056247 | 0.82 | FOLH1 (0.43) | FOLH1ALDH1A1L3MBTL1MCL1KDM4E | |
| SCHEMBL16416469 | 0.81 | TSHR (0.61) | FOLH1ALDH1A1L3MBTL1MCL1KDM4E | |
| SCHEMBL31056250 | 0.80 | PTGER1 (0.48) | POLBPTGER1MEN1KMT2ATHRB | |
| SCHEMBL31056681 | 0.80 | HTR2C (0.44) | L3MBTL1TDP1MEN1KMT2ASIRT1 | |
| SCHEMBL31056266 | 0.79 | HTR2C (0.46) | L3MBTL1TDP1MEN1KMT2ASIRT1 | |
| SCHEMBL31056082 | 0.79 | KDM1A (0.45) | SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |