Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31056412 | 0.91 | RXRA (0.42) | MCL1RXRARXRBRXRGPTGER1 | |
| SCHEMBL31056326 | 0.90 | RAB9A (0.44) | MCL1RXRARXRBRXRGFFAR4 | |
| SCHEMBL31056217 | 0.85 | FOLH1 (0.48) | MCL1PTGER1FOLH1L3MBTL1KDM4E | |
| SCHEMBL31056045 | 0.85 | PTGER1 (0.50) | MCL1RXRARXRBPTGER1FOLH1 | |
| SCHEMBL31056459 | 0.85 | FOLH1 (0.45) | MCL1RXRARXRBRXRGPTGER1 | |
| SCHEMBL31056250 | 0.82 | PTGER1 (0.48) | RXRARXRBRXRGPTGER1POLB | |
| SCHEMBL31056247 | 0.82 | FOLH1 (0.43) | MCL1PTGER1FOLH1L3MBTL1KDM4E | |
| SCHEMBL3112448 | 0.81 | RXRA (0.59) | MCL1RXRARXRBRXRGPTGER1 | |
| SCHEMBL31056705 | 0.81 | PTGER1 (0.40) | MCL1PTGER1FOLH1L3MBTL1EDNRA | |
| SCHEMBL31056266 | 0.81 | HTR2C (0.46) | FFAR4L3MBTL1MAPTCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |