Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325561 | 1.00 | CTSL (0.40) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL31056427 | 0.86 | CTSL (0.38) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL29325641 | 0.86 | CTSL (0.38) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL29320338 | 0.86 | CA12 (0.48) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL29321284 | 0.85 | ALDH1A1 (0.48) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL29320158 | 0.84 | CTSL (0.39) | CTSLCTSBCTSSCTSKSLC6A2 | |
| SCHEMBL17782196 | 0.82 | PARP1 (0.46) | — | |
| SCHEMBL17782195 | 0.82 | PARP1 (0.46) | — | |
| SCHEMBL31385923 | 0.80 | HTR2A (0.49) | HTR2A | |
| SCHEMBL25076663 | 0.79 | ALDH1A1 (0.36) | SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739675-A1 | INDOLE DERIVATIVES WITH FACTOR B INHIBITORY ACTIVITY | Sitala Bio Ltd (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008517-A1 | INDOLE DERIVATIVES WITH FACTOR B INHIBITORY ACTIVITY | SITALA BIO LTD (GB) | 2025-01-09 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |