Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056427 | 0.85 | CTSL (0.38) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL29320338 | 0.85 | CA12 (0.48) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL29325641 | 0.85 | CTSL (0.38) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL29321284 | 0.84 | ALDH1A1 (0.48) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL31056902 | 0.84 | CTSL (0.40) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL29325561 | 0.84 | CTSL (0.40) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL25076845 | 0.77 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL30988614 | 0.77 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL12488979 | 0.76 | ALDH1A1 (0.41) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29320165 | 0.74 | XIAP (0.34) | KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |