Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057599 | 0.85 | BCL2A1 (0.46) | TSPOALDH1A1CYP2A6NPC1RAB9A | |
| SCHEMBL25802749 | 0.81 | TSPO (0.46) | TSPONPC1RAB9ABCL2A1 | |
| SCHEMBL31288437 | 0.78 | TSPO (0.52) | TSPOALDH1A1NPC1RAB9AAPLNR | |
| SCHEMBL26694464 | 0.78 | TSPO (0.52) | TSPOALDH1A1NPC1RAB9AAPLNR | |
| SCHEMBL10787375 | 0.75 | ALDH1A1 (0.50) | TSPOALDH1A1APLNRCNR1CNR2 | |
| SCHEMBL10787385 | 0.75 | ALDH1A1 (0.47) | TSPOALDH1A1APLNRCNR1CNR2 | |
| SCHEMBL28490901 | 0.75 | NPC1 (0.56) | TSPOALDH1A1NPC1RAB9AAPLNR | |
| SCHEMBL31057531 | 0.75 | TSPO (0.40) | TSPOALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL24455917 | 0.74 | CYP2C19 (0.61) | TSPOALDH1A1APLNRCNR1CNR2 | |
| SCHEMBL11776874 | 0.74 | CYP2C19 (0.61) | TSPOALDH1A1APLNRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665735-A1 | KRAS INHIBITORS | Erasca, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2025245105-A1 | KRAS INHIBITORS | ERASCA, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2024173842-A1 | KRAS INHIBITORS | ERASCA, INC. (US) | 2024-08-22 | — | — | WO | disclosed |