Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057900 | 0.88 | MAPT (0.41) | RXFP1MAPTRAB9APOLBHPGD | |
| SCHEMBL31057922 | 0.79 | FPR2 (0.38) | MAPTPOLBALDH1A1KDM4EGABRA2 | |
| SCHEMBL31554478 | 0.65 | HPGD (0.56) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL8580742 | 0.64 | ALDH1A1 (0.54) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4402710 | 0.64 | RXFP1 (0.47) | RXFP1MAPTRAB9ANPC1POLB | |
| SCHEMBL27633504 | 0.64 | USP2 (0.49) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL29725710 | 0.64 | USP2 (0.49) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL28492711 | 0.64 | POLB (0.60) | RXFP1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4484802 | 0.64 | JAK2 (0.48) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27968221 | 0.63 | MAPT (0.53) | MAPTSMN1; SMN2POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |