Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057789 | 0.79 | RXFP1 (0.46) | TP53GABRA2GABRB2POLBLMNA | |
| SCHEMBL31057900 | 0.78 | MAPT (0.41) | TP53POLBLMNAMAPT | |
| SCHEMBL20595872 | 0.70 | FPR2 (0.42) | FPR2SYKHDAC6KDM4EALDH1A1 | |
| SCHEMBL18171825 | 0.69 | GRM2 (0.51) | SYKGRM2LMNAMAPTKDM4E | |
| SCHEMBL14876438 | 0.68 | PARK7 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3593243 | 0.68 | HDAC6 (0.40) | FPR2HDAC6POLBKDM4EALDH1A1 | |
| SCHEMBL3584044 | 0.68 | HDAC6 (0.43) | FPR2HDAC6POLBKDM4EALDH1A1 | |
| SCHEMBL15876278 | 0.66 | POLB (0.43) | POLBALDH1A1 | |
| SCHEMBL14876538 | 0.66 | CHRM5 (0.50) | SYKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL3584205 | 0.66 | GSK3A (0.46) | HDAC6POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |