Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057789 | 0.88 | RXFP1 (0.46) | MAPTRXFP1TP53POLBHPGD | |
| SCHEMBL31057922 | 0.78 | FPR2 (0.38) | MAPTTP53POLBLMNA | |
| SCHEMBL28567459 | 0.65 | TDP1 (0.57) | MAPTPOLBHPGDTDP1GAA | |
| SCHEMBL23121351 | 0.62 | ATM (0.41) | MAPTHPGDTDP1KMT2ATHRB | |
| SCHEMBL31057944 | 0.62 | CRHR1 (0.41) | MAPTPOLBTDP1GAAKMT2A | |
| SCHEMBL20595817 | 0.62 | KDM4E (0.42) | MAPTKMT2AHIF1ALMNARAB9A | |
| SCHEMBL31057912 | 0.62 | SHMT1 (0.74) | HPGDGAA | |
| SCHEMBL10587711 | 0.62 | PTGS1 (0.70) | MAPTTP53POLBHPGDKMT2A | |
| SCHEMBL24064509 | 0.61 | ALDH1A1 (0.68) | MAPTPOLBTDP1LMNARAB9A | |
| SCHEMBL23631652 | 0.61 | KMO (0.62) | POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |