Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.37 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458519 | 0.78 | MAPT (0.57) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL31718110 | 0.77 | JUN (0.40) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL31718111 | 0.77 | JUN (0.40) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL30637813 | 0.73 | PARP1 (0.43) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL31058347 | 0.73 | PARP1 (0.68) | PARP1CA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL31145448 | 0.69 | KIF11 (0.47) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL31138424 | 0.69 | KDM4E (0.40) | JUNNFKB1NFKB2RELAPARP1 | |
| SCHEMBL25955024 | 0.69 | TRPV1 (0.49) | PARP1KDM4ECA12CA9KIF11 | |
| SCHEMBL21248093 | 0.68 | KDM4E (0.58) | PARP1KDM4ECA12CA9KIF11 | |
| SCHEMBL3476605 | 0.68 | HDAC6 (0.49) | PARP1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |