Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.42 |
| ▸ | BRAF | P15056 | 4/20 | 0.40 |
| ▸ | TNKS | O95271 | 4/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429720 | 0.80 | HSD17B10 (0.55) | TRPV1TNKS2BRD4SCN5ASCN9A | |
| SCHEMBL18190547 | 0.74 | BRD4 (0.50) | TNKS2BRD4KDM4E | |
| SCHEMBL1458519 | 0.73 | MAPT (0.57) | PARP1KDM4ECA12CA9KIF11 | |
| SCHEMBL25429629 | 0.72 | TRPV1 (0.46) | TRPV1BRD4SCN5ASCN9AAR | |
| SCHEMBL28672016 | 0.72 | NCOA1 (0.62) | BRD4SCN9AKIF11AR | |
| SCHEMBL25429460 | 0.70 | KIF11 (0.53) | SCN9AKDM4EKIF11AR | |
| SCHEMBL25340003 | 0.69 | TRPV1 (0.38) | TRPV1SCN9AKDM4EARFEN1 | |
| SCHEMBL30868535 | 0.69 | BRAF (0.45) | BRAFBRD4SCN9A | |
| SCHEMBL31058401 | 0.69 | JUN (0.43) | TNKS2TNKSWNT3APARP1KDM4E | |
| SCHEMBL25429840 | 0.69 | PTGS2 (0.51) | BRD4SCN9ACA9KIF11AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |