Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019837 | 0.89 | GABRA1 (0.44) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL1050164 | 0.87 | CYP3A4 (0.47) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL1869397 | 0.86 | ALOX5 (0.46) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL132917 | 0.86 | ALOX5 (0.46) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL2843447 | 0.86 | ALOX5 (0.46) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL28387875 | 0.84 | ALOX5 (0.45) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL3739900 | 0.84 | GABRA1 (0.50) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| Acetic Acid SCHEMBL1657269 | 0.83 | PTGS1 (0.44) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL24242246 | 0.83 | CYP3A4 (0.46) | ALOX5CYP3A4ALDH1A1ARPTGS1 | |
| SCHEMBL22545546 | 0.83 | ALOX5 (0.44) | ALOX5CYP3A4ALDH1A1ARPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117947065-A | Construction method and application of engineering strain for producing methoxy eugenol | 江苏省中国科学院植物研究所 | 2024-04-30 | — | — | CN | claimed |
| US-20230416289-A1 | METHODS FOR ELECTROREDUCTIVE LIGNIN DEPOLYMERIZATION | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-12-28 | — | — | US | claimed |
| US-11267838-B2 | Methods for lignin depolymerization using thiols | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2022-03-08 | — | — | US | claimed |
| CN-103874432-B | Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles | R·J·雷诺兹烟草公司 | 2021-03-19 | — | — | CN | claimed |
| EP-3022281-B1 | PROCESS FOR REDUCING ETHANOL LOSS WHILE DEVELOPING DESIRABLE ORGANOLEPTICS DURING WOODEN BARREL AGING OF ALCOHOLIC BEVERAGE | CRYOVAC LLC (US) | 2020-03-11 | — | — | EP | claimed |
| US-10561168-B2 | Tobacco-derived components and materials | R.J. REYNOLDS TOBACCO COMPANY (US) | 2020-02-18 | — | — | US | claimed |
| US-20200048292-A1 | METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS | UNITED STATES DEPARTMENT OF ENERGY | 2020-02-13 | — | — | US | claimed |
| CN-105593356-B | Method for reducing ethanol loss while creating desirable organoleptic properties during wooden barrel aging of alcoholic beverages | 克里奥瓦克公司 | 2020-01-07 | — | — | CN | claimed |
| WO-2018195000-A1 | METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2018-10-25 | — | — | WO | claimed |
| US-9944891-B2 | Process for reducing ethanol loss while developing desirable organoleptics during wooden barrel aging of alcoholic beverage | CRYOVAC, INC. (US) | 2018-04-17 | — | — | US | claimed |
| US-8955523-B2 | Tobacco-derived components and materials | R.J. REYNOLDS TOBACCO COMPANY (US) | 2015-02-17 | — | — | US | claimed |
| US-20150037459-A1 | Process for Reducing Ethanol Loss While Developing Desirable Organoleptics During Wooden Barrel Aging of Alcoholic Beverage | CRYOVAC, INC. | 2015-02-05 | — | — | US | claimed |
| WO-2015010015-A2 | PROCESS FOR REDUCING ETHANOL LOSS WHILE DEVELOPING DESIRABLE ORGANOLEPTICS DURING WOODEN BARREL AGING OF ALCOHOLIC BEVERAGE | CRYOVAC, INC. (US) | 2015-01-22 | — | — | WO | claimed |
| EP-2709476-A2 | MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES | R. J. Reynolds Tobacco Company (US) | 2014-03-26 | — | — | EP | claimed |
| EP-2523568-B1 | TOBACCO-DERIVED COMPONENTS AND MATERIALS | REYNOLDS TOBACCO CO R (US) | 2013-12-18 | — | — | EP | claimed |
| US-20130014771-A1 | TOBACCO-DERIVED COMPONENTS AND MATERIALS | R. J. REYNOLDS TOBACCO COMPANY | 2013-01-17 | — | — | US | claimed |
| US-20120291793-A1 | MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES | R.J. REYNOLDS TOBACCO COMPANY | 2012-11-22 | — | — | US | claimed |
| WO-2012158915-A2 | MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES | R. J. REYNOLDS TOBACCO COMPANY (US) | 2012-11-22 | — | — | WO | claimed |
| EP-2523568-A2 | TOBACCO-DERIVED COMPONENTS AND MATERIALS | R. J. Reynolds Tobacco Company (US) | 2012-11-21 | — | — | EP | claimed |
| WO-2011088171-A2 | TOBACCO-DERIVED COMPONENTS AND MATERIALS | R. J. REYNOLDS TOBACCO COMPANY (US) | 2011-07-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267838-B2 | Methods for lignin depolymerization using thiols | DCXR, GLO1, LOX | ALOX5 155/4885CYP3A4 3029/4885ALDH1A1 454/4885 |
| US-20200048292-A1 | METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS | DCXR, GLO1, LOX | ALOX5 155/4885CYP3A4 3029/4885ALDH1A1 454/4885 |
| US-20230416289-A1 | METHODS FOR ELECTROREDUCTIVE LIGNIN DEPOLYMERIZATION | DCXR, LOX, ENGASE | ALOX5 121/4885CYP3A4 2261/4885ALDH1A1 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.