SCHEMBL2843447

SCHEMBL2843447

C=CCc1ccc(O)c(OC)c1CC=C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.46
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 1/20 0.46
AR P10275 1/20 0.46
PTGS1 P23219 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
GABRA1 P14867 8/20 0.46
GABRB2 P47870 8/20 0.46
CNR2 P34972 2/20 0.46
POLB P06746 3/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
GABRB1 P18505 1/20 0.40
RXRA P19793 1/20 0.40
CNR1 P21554 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1173287 0.90 ALOX5 (0.44) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL22545546 0.90 ALOX5 (0.44) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL11553229 0.87 ALOX5 (0.42) ALOX5CYP3A4ALDH1A1ARPTGS1
Methoxymethane SCHEMBL28899628 0.86 GABRA1 (0.41) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL29101603 0.86 ALOX5 (0.41) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL310587 0.86 ALOX5 (0.49) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL18035641 0.85 ALOX5 (0.43) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL874504 0.84 ALOX5 (0.42) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL3166964 0.84 SMPD1 (0.39) ALOX5CYP3A4ALDH1A1ARPTGS1
SCHEMBL1869397 0.83 ALOX5 (0.46) ALOX5CYP3A4ALDH1A1ARPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108587162-A A kind of non-autoclave molding prepreg bismaleimide resin and preparation method thereof 江苏恒神股份有限公司 2018-09-28 CN claimed
CN-116178717-B Preparation method of modified bismaleimide resin 华东理工大学 2025-04-15 CN disclosed
CN-117835831-A Flavor modulating composition 玉米产品开发公司 2024-04-05 CN disclosed
CN-116178717-A Preparation of modified bismaleimide resin 华东理工大学 2023-05-30 CN disclosed
CN-106589375-B A kind of modified bismaleimide resin and preparation method thereof 苏州大学 2019-04-05 CN disclosed
CN-108587162-A A kind of non-autoclave molding prepreg bismaleimide resin and preparation method thereof 江苏恒神股份有限公司 2018-09-28 CN disclosed
US-9497963-B2 Methods and compositions for control of gypsy moth, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2016-11-22 US disclosed
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2013-02-21 US disclosed
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR SIMON FRASER UNIVERSITY (CA) 2010-11-25 US disclosed
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar SIMON FRASER UNIVERSITY (CA) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar L3MBTL3, L3MBTL4, L3MBTL1 ALOX5 204/4885CYP3A4 2941/4885ALDH1A1 4074/4885
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar L3MBTL3, L3MBTL4, L3MBTL1 ALOX5 239/4885CYP3A4 2892/4885ALDH1A1 4132/4885
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR L3MBTL3, L3MBTL4, L3MBTL1 ALOX5 250/4885CYP3A4 2926/4885ALDH1A1 4180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.