SCHEMBL31059986

SCHEMBL31059986

CCc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(OC)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 4/20 0.36
KCNH2 Q12809 5/20 0.35
GCK P35557 4/20 0.35
PDE4B Q07343 2/20 0.35
PDE4A P27815 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
MALT1 Q9UDY8 1/20 0.35
DHODH Q02127 2/20 0.35
SLC2A1 P11166 2/20 0.34
SLC2A3 P11169 2/20 0.34
SLC2A4 P14672 2/20 0.34
SLC2A2 P11168 1/20 0.34
GPR6 P46095 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215215 0.90 PDE4B (0.38) KCNH2GCKPDE4BPDE4APDE4C
SCHEMBL31059982 0.89 DHODH (0.37) PDE4BMALT1DHODH
SCHEMBL31059992 0.83 DHODH (0.38) PDE4BPDE4APDE4CPDE4DMALT1
SCHEMBL29215014 0.81 ALDH1A1 (0.38) MALT1DHODH
SCHEMBL31059970 0.81 DHODH (0.40) PDE4BPDE4APDE4CPDE4DMALT1
SCHEMBL15147427 0.81 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL31060075 0.81 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL16564329 0.81 PDE4A (0.38) KCNH2GCKPDE4BPDE4APDE4C
SCHEMBL15971540 0.81 SLC2A1 (0.38) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL31060054 0.81 DHODH (0.40) MALT1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 PDE5A 461/4885KCNH2 1159/4885GCK 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.