SCHEMBL29215215

SCHEMBL29215215

COc1cc(C(=O)Nc2c(C)cc(C#N)cc2C(N)=O)n(-c2ncccc2Cl)n1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 2/20 0.38
PDE4A P27815 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
SLC2A1 P11166 5/20 0.37
SLC2A3 P11169 5/20 0.37
SLC2A4 P14672 5/20 0.37
SLC2A2 P11168 2/20 0.37
DHODH Q02127 3/20 0.35
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.34
GCK P35557 2/20 0.33
KCNH2 Q12809 2/20 0.33
MALT1 Q9UDY8 2/20 0.33
GPR6 P46095 1/20 0.33
RBP4 P02753 1/20 0.33
CHRNA7 P36544 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15971540 0.90 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL31059986 0.90 PDE5A (0.36) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL959387 0.90 DHODH (0.42) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL31059983 0.90 DHODH (0.42) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL29377007 0.90 DHODH (0.42) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL29215014 0.90 ALDH1A1 (0.38) DHODHMALT1RBP4CHRNA7
SCHEMBL31060063 0.90 SLC2A1 (0.38) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL961226 0.90 SLC2A1 (0.38) PDE4BPDE4APDE4CPDE4DSLC2A1
SCHEMBL15147427 0.89 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL31060075 0.89 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed
EP-4380363-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-12 EP disclosed
CN-118076228-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-05-24 CN disclosed
WO-2023012081-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 PDE4B 837/4885PDE4A 1594/4885PDE4C 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.