Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728199 | 0.71 | ALDH1A1 (0.39) | LMNAGAACSF1RKDRCDK5 | |
| SCHEMBL8999359 | 0.70 | LRRK2 (0.35) | ACHEMKNK1MKNK2 | |
| SCHEMBL544598 | 0.69 | MAP4K4 (0.48) | GSK3BACHEMKNK1MKNK2LMNA | |
| SCHEMBL5236193 | 0.64 | ALDH1A1 (0.68) | GSK3BLMNAGAACSF1RKDR | |
| SCHEMBL218119 | 0.64 | ALOX15 (0.52) | LMNAGAAKDRMAPTGFER | |
| SCHEMBL2581914 | 0.61 | BACE1 (0.44) | LMNACSF1RKDRCDK5CLK4 | |
| SCHEMBL3379956 | 0.61 | AKT2 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL28197453 | 0.61 | ALOX15 (0.43) | LMNAGAACSF1RKDRCDK5 | |
| SCHEMBL25272042 | 0.61 | CYP2A6 (0.43) | LMNACSF1RKDRCDK5CLK4 | |
| SCHEMBL6971232 | 0.61 | AKT1 (0.39) | GSK3BMKNK2LMNAPIM1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |