Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882339 | 0.84 | SQOR (0.32) | AKT1AKT2ALDH1A1ALOX15SQOR | |
| SCHEMBL1384959 | 0.83 | SQOR (0.51) | AKT1AKT2ALDH1A1SQORMAP4K4 | |
| SCHEMBL25274257 | 0.80 | METAP2 (0.43) | AKT1AKT2ALDH1A1ALOX15SQOR | |
| SCHEMBL3263121 | 0.79 | MAPK1 (0.43) | ALDH1A1SQORMAP4K4CSF1RFGFR1 | |
| SCHEMBL10432295 | 0.79 | ALDH1A1 (0.39) | ALDH1A1PARP1LMNAL3MBTL1BACE1 | |
| SCHEMBL1386288 | 0.79 | NPC1 (0.35) | AKT1AKT2ALDH1A1ALOX15SQOR | |
| SCHEMBL1386673 | 0.77 | SQOR (0.49) | ALDH1A1SQORCDC7CDK1CDK2 | |
| SCHEMBL218119 | 0.77 | ALOX15 (0.52) | AKT1AKT2ALDH1A1ALOX15KDR | |
| SCHEMBL28911214 | 0.76 | BCAT2 (0.41) | ALDH1A1MAP4K4CSF1RFGFR1KDR | |
| SCHEMBL544598 | 0.76 | MAP4K4 (0.48) | AKT1AKT2ALDH1A1ALOX15MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074551-B1 | Phenylpyrazoles with a herbicidal activity | ISAGRO RICERCA SRL (IT) | 2003-03-26 | — | — | EP | claimed |
| US-6265351-B1 | CONTROLLING WEEDS IN THE AGRONOMIC FIELD. | ISAGRO RICERCA S.R.L. (IT) | 2001-07-24 | — | — | US | claimed |
| EP-1074551-A2 | Phenylpyrazoles with a herbicidal activity | Isagro Ricerca S.r.l. (IT) | 2001-02-07 | — | — | EP | claimed |
| EP-1074551-B1 | Phenylpyrazoles with a herbicidal activity | ISAGRO RICERCA SRL (IT) | 2003-03-26 | — | — | EP | disclosed |
| US-6265351-B1 | CONTROLLING WEEDS IN THE AGRONOMIC FIELD. | ISAGRO RICERCA S.R.L. (IT) | 2001-07-24 | — | — | US | disclosed |
| EP-1074551-A2 | Phenylpyrazoles with a herbicidal activity | Isagro Ricerca S.r.l. (IT) | 2001-02-07 | — | — | EP | disclosed |