Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLUL | P15104 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.34 |
| ▸ | OTC | P00480 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981869 | 0.91 | GLUL (0.37) | GLULNOS2NOS1NOS3BHMT | |
| SCHEMBL2981858 | 0.91 | GLUL (0.37) | GLULNOS2NOS1NOS3BHMT | |
| SCHEMBL2981882 | 0.91 | GLUL (0.37) | GLULNOS2NOS1NOS3BHMT | |
| Cystine SCHEMBL30234178 | 0.76 | GLUL (0.44) | GLULNOS2NOS1NOS3BHMT | |
| SCHEMBL15548560 | 0.74 | SLC7A5 (0.41) | GLUL | |
| SCHEMBL15548558 | 0.74 | SLC7A5 (0.41) | GLUL | |
| SCHEMBL2992209 | 0.73 | BHMT (0.47) | GLULNOS2NOS1NOS3BHMT | |
| SCHEMBL2992203 | 0.73 | BHMT (0.47) | GLULNOS2NOS1NOS3BHMT | |
| SCHEMBL9703082 | 0.72 | NOS2 (0.47) | NOS2NOS1NOS3BHMTARG1 | |
| SCHEMBL29008680 | 0.72 | NOS2 (0.47) | NOS2NOS1NOS3BHMTARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |