Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | CCNC | P24863 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | TNKS | O95271 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16521506 | 0.82 | ADORA3 (0.69) | ADORA3ARCCNCCDK8MAOB | |
| SCHEMBL25449242 | 0.79 | AR (0.73) | ADORA3ARCCNCCDK8MAOB | |
| SCHEMBL12636897 | 0.76 | CYP1B1 (0.81) | ARCCNCCDK8MAOBTNKS | |
| SCHEMBL7606268 | 0.76 | PTGS2 (0.61) | ADORA3ARCCNCCDK8MAOB | |
| SCHEMBL17265620 | 0.75 | ABCB1 (0.80) | ADORA3ARCCNCCDK8MAOB | |
| SCHEMBL28588011 | 0.75 | CSNK2A2 (0.61) | ADORA3ARCCNCCDK8MAOB | |
| SCHEMBL12636899 | 0.74 | AR (1.00) | ARCCNCCDK8MAOBTNKS | |
| SCHEMBL15268315 | 0.74 | MAOB (0.68) | ADORA3CDK8MAOBTNKSTNKS2 | |
| SCHEMBL11856359 | 0.73 | ADORA3 (0.57) | ADORA3ARMAOBTNKSPARP1 | |
| SCHEMBL17265616 | 0.73 | ABCB1 (0.81) | ADORA3ARCCNCCDK8TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |