Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | CCNC | P24863 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449242 | 0.77 | AR (0.73) | ADORA3ARCCNCCDK8CSNK2A2 | |
| SCHEMBL16521506 | 0.76 | ADORA3 (0.69) | PTGS2ADORA3ARCCNCCDK8 | |
| SCHEMBL31060888 | 0.76 | ADORA3 (1.00) | PTGS2ADORA3ARCCNCCDK8 | |
| SCHEMBL28588026 | 0.75 | CYP3A4 (0.62) | ADORA3CSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL14749128 | 0.74 | MAPT (0.73) | PTGS2ADORA3ARCDK8CSNK2A2 | |
| SCHEMBL12636897 | 0.73 | CYP1B1 (0.81) | PTGS2ARCCNCCDK8CSNK2A2 | |
| SCHEMBL28568538 | 0.73 | CYP3A4 (0.72) | PTGS2ADORA3ARCCNCCDK8 | |
| SCHEMBL12636899 | 0.71 | AR (1.00) | ARCCNCCDK8CYP3A4MAPT | |
| SCHEMBL13479744 | 0.71 | CSNK2A2 (0.64) | ADORA3ARCCNCCDK8CSNK2A2 | |
| SCHEMBL20664412 | 0.71 | ADORA3 (0.76) | ADORA3CDK8CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413998-B1 | BONE REGENERATION | OSTEOSCREEN, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6008208-A | Compositions and methods for treating bone deficit conditions | OSTEOSCREEN, INC. (US) | 1999-12-28 | — | — | US | disclosed |