SCHEMBL31063173

SCHEMBL31063173

COc1c(F)cc(C(C)C)cc1B(O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EIF4A3 P38919 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
TUBB4A P04350 2/20 0.31
TUBB P07437 2/20 0.31
TUBA3C P0DPH7 2/20 0.31
TUBA1B P68363 2/20 0.31
TUBA4A P68366 2/20 0.31
TUBB4B P68371 2/20 0.31
TUBB3 Q13509 2/20 0.31
TUBB2A Q13885 2/20 0.31
TUBB8 Q3ZCM7 2/20 0.31
TUBA3E Q6PEY2 2/20 0.31
TUBA1A Q71U36 2/20 0.31
TUBA1C Q9BQE3 2/20 0.31
TUBB6 Q9BUF5 2/20 0.31
TUBB2B Q9BVA1 2/20 0.31
TUBB1 Q9H4B7 2/20 0.31
CACNA1H O95180 1/20 0.31
FABP3 P05413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL801223 0.82 EIF4A3 (0.41) EIF4A3GABRA1GABRB2TUBB1CACNA1H
SCHEMBL31075874 0.82
SCHEMBL31076231 0.82
SCHEMBL31075932 0.81 PDE2A (0.36) EIF4A3GABRA1GABRB2
SCHEMBL31063473 0.81 PTGS2 (0.35) EIF4A3GABRA1GABRB2PTGS2
SCHEMBL4858958 0.80 GABRA1 (0.41) GABRA1GABRB2TUBB4ATUBBTUBA3C
SCHEMBL2467633 0.77 TUBB1 (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31063422 0.76 ACHE (0.40) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL12190511 0.76 EIF4A3 (0.33) EIF4A3GABRA1GABRB2CACNA1H
SCHEMBL17622095 0.76 TAAR1 (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
EP-4665458-A1 INHIBITING ALPHA V BETA8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
WO-2024173570-A1 INHIBITING αvβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed
WO-2024173572-A1 INHIBITING α vβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed