⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075874 | 1.00 | — | — | |
| SCHEMBL31063173 | 0.82 | EIF4A3 (0.34) | — | |
| SCHEMBL31076303 | 0.78 | CA2 (0.35) | — | |
| SCHEMBL31075765 | 0.78 | CA2 (0.35) | — | |
| SCHEMBL31063030 | 0.71 | DBH (0.34) | — | |
| SCHEMBL2467633 | 0.71 | TUBB1 (0.34) | — | |
| SCHEMBL2393968 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL24974307 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL31063422 | 0.70 | ACHE (0.40) | — | |
| SCHEMBL17622095 | 0.70 | TAAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |