Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19129605 | 0.84 | CA2 (0.59) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30526544 | 0.82 | MAPT (0.54) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4696875 | 0.82 | MAPT (0.54) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL27709205 | 0.79 | CA2 (0.48) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| SCHEMBL21402282 | 0.79 | ALOX15 (0.65) | GAAKMT2AMEN1LMNATSHR | |
| SCHEMBL12293826 | 0.79 | HTT (0.53) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15549114 | 0.77 | CYP1A2 (0.41) | ALDH1A1KDM4ETSHR | |
| SCHEMBL15259675 | 0.77 | CALM1 (0.55) | MAPTSMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL1613836 | 0.77 | MAPT (0.37) | MAPT | |
| SCHEMBL8294365 | 0.76 | MAPT (0.49) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |